Delete Local Settings Temp Files

http://www.winforumz.com/windows/TIF-subfolder-inside-Temp-folder-Local-Settings-Safe-ftopict590111.html (TIF subfolder inside Temp folder at Local Settings--Safe t..)
Hello: At Documents and Settings-->User Name-->Local Settings, I have a subfolder named: Temp. In it, there is another subfolder named: "Temporary Internet Files", which in turn contains another subfolder named: "Content. IE5". Can I safely delete that entire TIF subfolder, or just its contents..
« Hi, It's safer to clear the cache (TIF) through the browser's options. But, it should be safe to delete a Temporary Internet Files folder- it will be recreated on restart. Hope this helps, Don »
« Go to Internet Options> General> Temporary Internet Files> Settings. What's the current location of the Temporary Internet Files folder? If your TIF folder is at (you will have to be able to see hi.. »
« General> Temporary Internet Files> Settings. What's the current location of the Temporary Internet Files folder? If your TIF folder is at (you will have to be able to see hidden and system files) I.. »

http://www.winforumz.com/windows/deleting-contents-Local-Settings-Temp-ftopict600469.html (deleting contents of Local Settings/Temp)
I am cleaning my HD. In Documents and Settings/myName/Local Settings/ there is a folder called Temp which if about 650Mb If I delete its contents, leaving the folder in place, how it will affect the work of XP?
« Best to purge it's contents immediately after a boot. But generally, there is no downside to periodically cleaning it out. The same with the System Temp folder found at WindowsTemp. Be aware that .. »
« Thanks. Some files indeed refuse to get deleted saying that they are being used by another application. How do I delete these? Also I got a message that folders Cookie and History in Temp folder are.. »
« While XP is running, there are always applications/services that require workspace ( Think of it as a computer's Scratch Pad). Those files will always be there and open. Zone Alarm Free will have a .. »